Amino-Dibenz[b,f][[1,4]Oxazepine-11(10H)-Ones

  • Inventors:
  • Assignees: Thomae Gmbh Dr K
  • Publication Date: September 17, 1969
  • Publication Number: GB-1164579-A

Abstract

1,164,579. Analgesic &c. medicines. DR. KARL THOMAE G.m.b.H. 11 July, 1968 [11 July, 1967], No. 33186/68. Heading A5B. [Also in Division C2] Pharmaceutical preparations showing analgesic, antipyretic and sedative activity contain as an active ingredient compounds of the general formula: wherein R 1 signifies a hydrogen atom or a straight or branched alkyl group, R 2 ' signifies a hydrogen or halogen atom or an alkyl group and one of R 3 and R 4 signifies NH 2 whilst the other signifies a hydrogen atom. Other active substances such as caffeine, acetyl-salicylic acid, antiphlogistics, e.g., 1,2-diphenyl-3,5- dioxo-4-n-butylpyrazolidine, dormifacients, e.g. 5-(1-cycloheptenyl)-5-ethyl-barbituric acid or secretolytics, e.g., N-(2-amino-3,5-dibromobenzyl)-N-methyl-cyclohexyl ammonium chloride may also 'be included in the preparations. Granules, tablets, coated tablets, capsules, syrups, emulsions, suspensions, drops, ampoules or suppositories are suitable forms for administration, i.e.- - orally, parenterally or rectally.

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    Publication numberPublication dateAssigneeTitle
    US-5173486-ADecember 22, 1992Bristol-Myers Squibb CompanyDibenz[b,f][1,4]oxazepin-11(10H)-ones for multidrug resistance reversing agents