Process for preparation of 1-(2'-hydroxyethyl)-2-methyl-5-nitroimidazole

  • Inventors:
  • Assignees: K R K A Tovarna Zdravil
  • Publication Date: January 01, 1969
  • Publication Number: GB-1138805-A

Abstract

1,138,805. 1 - (2<SP>1</SP> - Hydroxyethyl) - 2 - methyl- 5-nitroimidazole. K.R.K.A. TOVARNA ZDRAVIL. 31 May, 1967 [20 June, 1966], No. 25021/67. Heading C2C. 1 - (2<SP>1 </SP>- Hydroxyethyl) - 2 - methyl - 5 - nitroimidazole is prepared by hydrolysis of a 1 - (2<SP>1 </SP>- halogenoethyl) - 2 - methyl - 5 - nitroimidazole of the formula wherein X is a halogen atom, preferably by means of formamide in the presence of water and formic acid. Reference has been directed by the Comptroller to Specification 836,854.

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